阐释方药治疗慢阻肺特征，揭示方药物质基础与机制；构建组分配伍研究平台，形成组分方剂。
（1）Li Ya, Li Jiansheng, Li Weiwei, Li Suyun, Tian Yange, Lu Xiaofan, Jiang Suli, Wang Ying. Long-term effects of three Tiao-Bu Fei-Shen therapies on NF-κB/TGF-β1/smad2 signaling in rats with chronic obstructive pulmonary disease. BMC Complement Altern Med. 2014, 14:140.
（2）Li Jiansheng, Zhao Peng, Li Ya, Tian Yange, Wang Yonghua. Systems pharmacology-based dissection of mechanisms of Chinese medicinal formula Bufei Yishen as an effective treatment for chronic obstructive pulmonary disease. Sci Rep. 2015, 5:15290.
（3）Zhao Peng, Yang Liping, Li Jiansheng, Li Ya, Tian Yange, Li Suyun. Combining systems pharmacology, transcriptomics, proteomics, and metabolomics to dissect the therapeutic mechanism of Chinese herbal Bufei Jianpi formula for application to COPD. Int J Chron Obstruct Pulmon Dis. 2016, 11:553-566.
（4）Zhao Peng, LiJ iansheng, Tian Yange, Mao Jing, Liu Xuefang, Feng Suxiang, Li Junzi, Bian Qingqing, Ji Huige, Zhang Lanxi. Restoring Th17/Treg balance via modulation of STAT3 and STAT5 activation contributes to the amelioration of chronic obstructive pulmonary disease by Bufei Yishen formula. J Ethnopharmacol. 2018, 217:152-162.
（5）Li Jiansheng, Xie Yang, Zhao Peng, Qin Yanqin, Brian G Oliver, Tian Yange, Li Suyun, Wang Minghang, Liu Xuefang. A chinese herbal formula ameliorates COPD by inhibiting the inflammatory response via downregulation of p65, JNK, and p38. Phytomedicine. 2021, 83:153475.
（6）Li Jiansheng, Wang Jing, Li Ya, Zhao Peng, Tian Yange, Liu Xuefang, He Huihui, Jia Rui. Effective-component compatibility of Bufei Yishen formula protects COPD rats against PM2.5-induced oxidative stress via miR-155/FOXO3a pathway. Ecotoxicol Environ Saf. 2021, 228:112918.
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